Description

4-Cyclopropylbenzene-1-Sulfonyl Chloride is a versatile and reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, enabling the efficient introduction of the 4-cyclopropylphenylsulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with the cyclopropylphenylsulfonyl group.
• Material Science Research: Used in the development of specialty polymers and functional materials requiring specific sulfonyl groups.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates.

Basic Information

Product Name	4-Cyclopropylbenzene-1-Sulfonyl Chloride
CAS No.	167404-32-2
Molecular Formula	C9H9ClO2S
Molecular Weight	216.68 g/mol
Synonyms	4-Cyclopropylbenzenesulfonyl chloride; p-Cyclopropylbenzenesulfonyl chloride; (4-Cyclopropylphenyl)sulfonyl chloride; 1-Cyclopropyl-4-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 4-cyclopropyl-; 4-CPS-Cl
EINECS	Contact for details

Quality Control

Our 4-Cyclopropylbenzene-1-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analysis, including chromatographic purity assessment and identity confirmation. A Certificate of Analysis (COA) detailing specific results for assay, impurities, and physical properties is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.