Description

2-Methyl-4'-(Trifluoromethyl)-1,1'-Biphenyl is a high-value biphenyl derivative distinguished by its methyl and trifluoromethyl substituents, which impart unique electronic and steric properties. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a core structural motif in the development of new-generation herbicides and fungicides, leveraging the stability of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Used as a precursor in the manufacture of liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) due to its rigid biphenyl core and fluorine content.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) to construct more complex polyaromatic systems for material science research.
• Ligand & Catalyst Development: Acts as a scaffold for creating specialized ligands in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	2-Methyl-4'-(Trifluoromethyl)-1,1'-Biphenyl
CAS No.	167021-49-0
Molecular Formula	C14H11F3
Molecular Weight	236.24 g/mol
Synonyms	2-Methyl-4'-(trifluoromethyl)biphenyl; 4'-(Trifluoromethyl)-2-methylbiphenyl; 1,1'-Biphenyl, 2-methyl-4'-(trifluoromethyl)-; 2-Methyl-4'-trifluoromethylbiphenyl; 2-Methyl-4'-(trifluoromethyl)diphenyl; [1,1'-Biphenyl]-2-methyl-4'-(trifluoromethyl)-; α-Methyl-4'-(trifluoromethyl)biphenyl
EINECS	Contact for details

Quality Control

Our 2-Methyl-4'-(Trifluoromethyl)-1,1'-Biphenyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.