Description

5-(Phenylsulfonyl)Thiophene-2-Sulfonyl Chloride is a high-value, multi-functional sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a phenylsulfonyl and a reactive sulfonyl chloride group on a thiophene ring, makes it an essential intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas targeting enzymes and receptors where the thiophene-sulfonamide pharmacophore is valuable.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its ability to introduce sulfonamide functionalities.
• Functional Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, dyes, and organic electronic materials.
• Chemical Biology Probe Development: Employed to create activity-based probes or affinity labels for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	5-(Phenylsulfonyl)Thiophene-2-Sulfonyl Chloride
CAS No.	166964-37-0
Molecular Formula	C10H7ClO4S3
Molecular Weight	346.80 g/mol
Synonyms	2-Thiophenesulfonyl chloride, 5-(phenylsulfonyl)-; 5-(Benzenesulfonyl)thiophene-2-sulfonyl chloride; 5-(Phenylsulfonyl)-2-thiophenesulfonyl chloride; Thiophene-2,5-disulfonyl chloride, 2-phenylsulfonyl derivative; 166964-37-0; 5-Phenylsulfonylthiophene-2-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-(Phenylsulfonyl)Thiophene-2-Sulfonyl Chloride is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure compliance with industry standards for fine chemical intermediates. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.