Description

2-[1-Methyl-5-(Trifluoromethyl)Pyrazol-3-Yl]-Thiophene-5-Sulfonyl Chloride is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its unique heterocyclic structure, which incorporates both a pyrazole and a thiophene ring, making it a versatile building block for creating complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole-thiophene scaffold.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in medicinal chemistry for creating labeled compounds and probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2-[1-Methyl-5-(Trifluoromethyl)Pyrazol-3-Yl]-Thiophene-5-Sulfonyl Chloride
CAS No.	166964-31-4
Molecular Formula	C9H6F3N3O2S2Cl
Molecular Weight	345.74 g/mol
Synonyms	5-Thiophenesulfonyl chloride, 2-[1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-; 2-(1-Methyl-5-trifluoromethyl-1H-pyrazol-3-yl)thiophene-5-sulfonyl chloride; 3-(5-Chlorosulfonyl-2-thienyl)-1-methyl-5-(trifluoromethyl)pyrazole; 166964-31-4; 2-[1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophene-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-[1-Methyl-5-(Trifluoromethyl)Pyrazol-3-Yl]-Thiophene-5-Sulfonyl Chloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and meet the exacting standards required for pharmaceutical and agrochemical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.