Description

(E)-3-[1-[4-[2-(Dimethylamino)Ethoxy]Phenyl]-2-Phenyl-1-Butenyl]Phenyl β-D-Glucopyranosiduronic Acid is a high-purity, complex organic compound of significant interest in advanced pharmaceutical research and development. Its core value lies in its role as a key metabolite or synthetic intermediate for novel therapeutic agents, particularly in areas requiring targeted biological activity. This product is essential for B2B clients in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for drug discovery, process development, and analytical reference standards.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel drug candidates, particularly in oncology and endocrine therapy research.
• Metabolite Reference Standard: Used in analytical laboratories for the identification and quantification of drug metabolites in bioanalytical studies (e.g., LC-MS, HPLC).
• Biochemical Research: Serves as a tool compound for studying enzyme interactions, metabolic pathways, and receptor binding assays.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for active pharmaceutical ingredients (APIs).
• Quality Control & Regulatory Compliance: Provides an authentic standard for method validation, impurity profiling, and regulatory filings (e.g., FDA, EMA).

Basic Information

Product Name	(E)-3-[1-[4-[2-(Dimethylamino)Ethoxy]Phenyl]-2-Phenyl-1-Butenyl]Phenyl β-D-Glucopyranosiduronic Acid
CAS No.	165460-33-3
Molecular Formula	C34H39NO8
Molecular Weight	589.68 g/mol
Synonyms	Tamoxifen Metabolite E; (Z)-Endoxifen Glucuronide; Afimoxifene Glucuronide; 4-Hydroxy-N-desmethyltamoxifen β-D-Glucuronide; (E)-Endoxifen Glucuronide; NSC 759836; 1-Buten-1-one, 1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-, 4-(β-D-glucopyranuronosyloxy)phenyl deriv.
EINECS	Contact for details

Quality Control

Our (E)-3-[1-[4-[2-(Dimethylamino)Ethoxy]Phenyl]-2-Phenyl-1-Butenyl]Phenyl β-D-Glucopyranosiduronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.