Description

Trichloro Acetyl-13C2 Chloride is a stable isotope-labeled derivative of trichloroacetyl chloride, specifically enriched with carbon-13 at two positions. This compound is a critical reagent for the synthesis of isotopically labeled molecules, enabling precise tracking and quantification in analytical and metabolic studies. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-fidelity isotopic labeling for applications in mass spectrometry, NMR spectroscopy, and tracer studies.

Application

• Pharmaceutical Research & Development: Synthesis of carbon-13 labeled active pharmaceutical ingredients (APIs) and intermediates for drug metabolism and pharmacokinetics (DMPK) studies.
• Analytical Chemistry Standards: Used as a precursor for preparing internal standards for quantitative analysis via LC-MS and GC-MS, improving accuracy and reliability.
• Metabolic Pathway Tracing: Key building block for creating probes to study biochemical pathways and mechanisms in biological systems.
• Agrochemical Development: Incorporation into isotopically labeled pesticides or herbicides for environmental fate and residue analysis studies.
• Advanced Material Science: Potential use in the synthesis of specialty polymers or organic electronic materials where isotopic purity influences physical properties.
• NMR Spectroscopy: Serves as a starting material for synthesizing NMR shift reagents or labeled compounds to simplify complex spectral analysis.

Basic Information

Product Name	Trichloro Acetyl-13C2 Chloride
CAS No.	165399-57-5
Molecular Formula	C13CCl3OCl or CCl313COCl
Molecular Weight	~185.83 g/mol (for 13C2 labeled)
Synonyms	Trichloroacetyl-13C2 Chloride; [13C2]-Trichloroacetyl Chloride; Carbon-13 Labeled Trichloroacetyl Chloride; 2,2,2-Trichloroacetyl-13C2 Chloride; Trichloroacetic-13C2 Chloride; Perchloroacetyl-13C2 Chloride; TCA-13C2 Chloride
EINECS	Contact for details

Quality Control

Our Trichloro Acetyl-13C2 Chloride is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical identity. We provide comprehensive Certificates of Analysis (COA) detailing purity, isotopic abundance, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts violently with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (13C2)	≥ 99 atom % 13C
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.