Description

L-(+)-Swainsonine is a potent and specific inhibitor of Golgi α-mannosidase II, a key enzyme in N-linked glycoprotein processing. This high-purity compound is essential for researchers and developers in life sciences, enabling the study of glycosylation pathways and their role in cellular communication and disease. It is a critical tool for biochemical research, pharmaceutical development, and the production of high-value fine chemicals.

Application

• Biochemical Research: Used as a selective inhibitor to study N-linked oligosaccharide processing, lysosomal storage disorders, and glycoprotein function in cell biology.
• Pharmaceutical Development: Serves as a reference standard and a key intermediate in the research and development of novel therapeutics targeting glycosylation-related diseases.
• Glycobiology Studies: Essential for investigating the biological roles of complex carbohydrates in immunology, virology, and cancer metastasis.
• Enzyme Inhibition Assays: Employed in high-throughput screening and in vitro assays to evaluate the activity of mannosidase enzymes and discover new inhibitors.
• Fine Chemical Synthesis: Acts as a chiral building block or a sophisticated intermediate in the synthesis of complex natural products and specialized research chemicals.

Basic Information

Product Name	L-(+)-Swainsonine
CAS No.	164907-52-2
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	(1S,2R,8R,8aR)-1,2,8-Trihydroxyoctahydroindolizine; Swainsonine, L-(+)-form; (+)-Swainsonine; Swainsonine; (8aβ)-1,2,8-Trihydroxyoctahydroindolizine; L-Swainsonine; Indolizidine-1,2,8-triol, (1S,2R,8R,8aR)-
EINECS	Contact for details

Quality Control

Our L-(+)-Swainsonine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	[α]20/D +80° to +85° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.