Description

Magnesium,2-Phenyl-1,3-Dioxolane,Bromide CAS NO 164718-49-4 is a highly reactive organomagnesium reagent, specifically a Grignard reagent, where the magnesium center is complexed with a 2-phenyl-1,3-dioxolane protecting group. This compound is a critical synthetic intermediate for the controlled formation of carbon-carbon bonds in complex organic synthesis. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for constructing chiral molecules, active pharmaceutical ingredients (APIs), and advanced material precursors.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for the production of chiral drugs and complex bioactive molecules.
• Asymmetric Catalysis & Ligand Preparation: Used in the synthesis of chiral ligands and catalysts for stereoselective reactions.
• Fine Chemical Manufacturing: Enables precise carbon chain elongation and functional group introduction in specialty chemicals.
• Academic & Industrial R&D: Essential reagent for methodological development in organic and medicinal chemistry research.
• Agrochemical Synthesis: Intermediate in the creation of advanced, targeted pesticide and herbicide molecules.
• Material Science Precursors: Used to synthesize organic components for electronic materials and polymers.

Basic Information

Product Name	Magnesium,2-Phenyl-1,3-Dioxolane,Bromide
CAS No.	164718-49-4
Molecular Formula	C9H9BrMgO2
Molecular Weight	253.38 g/mol
Synonyms	2-Phenyl-1,3-dioxolane magnesium bromide; (2-Phenyl-1,3-dioxolan-2-yl)magnesium bromide; Magnesium, bromo(2-phenyl-1,3-dioxolan-2-yl)-; Phenylacetaldehyde ethylene acetal Grignard reagent; Bromo(2-phenyl-1,3-dioxolan-2-yl)magnesium; Grignard reagent of phenylacetaldehyde ethylene acetal; 2-(Bromomagnesio)-2-phenyl-1,3-dioxolane
EINECS	Contact for details

Quality Control

Every batch of our Magnesium,2-Phenyl-1,3-Dioxolane,Bromide is manufactured and handled under strict inert atmosphere conditions to ensure reactivity and purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing assay, titration, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this material must be stored under an inert atmosphere (argon or nitrogen) at temperatures between 2°C and 8°C. Keep the container in a cool, dry, well-ventilated place, away from incompatible materials such as strong acids, oxidizers, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typically in THF or Ether)
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M to 2.0 M in solvent (Custom concentrations available)
Purity (GC/HPLC)	≥ 95% (by GC, area %)
Water Content (KF)	≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.