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(17β)-n-[2,5-Bis(Trifluoromethyl)Phenyl]-3-Oxo-4-Azaandrost-5-Ene-17-Carboxamide CAS NO 164656-21-7


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CAS No.:164656-21-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(17β)-n-[2,5-Bis(Trifluoromethyl)Phenyl]-3-Oxo-4-Azaandrost-5-Ene-17-Carboxamide is a high-purity, non-steroidal synthetic compound of significant interest in advanced pharmaceutical research and development. Its unique molecular architecture, featuring a modified steroidal backbone and trifluoromethylphenyl substituents, makes it a valuable intermediate for creating novel therapeutic agents. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new drug candidates targeting specific hormonal pathways and receptors.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathway for novel active pharmaceutical ingredients (APIs), particularly in hormonal and metabolic disorder research.
  • Biochemical Research: Used as a reference standard or probe compound in studies investigating enzyme inhibition, receptor binding affinity, and structure-activity relationships (SAR).
  • Preclinical Development: Employed in the early-stage development of potential drug candidates for efficacy and safety profiling.
  • Academic Research: Utilized in university and institutional laboratories for fundamental studies in medicinal chemistry and organic synthesis.
  • Contract Research Organizations (CROs): Supplied to CROs conducting specialized client-sponsored research requiring high-purity, well-characterized chemical entities.

Basic Information

Product Name (17β)-n-[2,5-Bis(Trifluoromethyl)Phenyl]-3-Oxo-4-Azaandrost-5-Ene-17-Carboxamide
CAS No. 164656-21-7
Molecular Formula C29H30F6N2O2
Molecular Weight 552.56 g/mol
Synonyms 4-Azaandrost-5-ene-17-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-, (17β)-; BMS-564929; Androgen Receptor Modulator BMS-564929; (17β)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-5-ene-17-carboxamide; UNII-5Q6K25520G; 5Q6K25520G; BMS564929
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Quality Control

Every batch of (17β)-n-[2,5-Bis(Trifluoromethyl)Phenyl]-3-Oxo-4-Azaandrost-5-Ene-17-Carboxamide is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for research chemicals. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to confirm identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Residual Solvents (GC) Complies with ICH guidelines
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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