Description

5-(Trifluoromethyl)-2-Pyridinemethanamine is a high-purity trifluoromethylated pyridine derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the reactive primary amine functionality, enabling precise molecular modifications. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often improves metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor for constructing specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials due to its fluorine-containing aromatic structure.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation and the development of molecular probes and fluorescent tags.

Basic Information

Product Name	5-(Trifluoromethyl)-2-Pyridinemethanamine
CAS No.	164341-39-3
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	2-(Aminomethyl)-5-(trifluoromethyl)pyridine; [5-(Trifluoromethyl)pyridin-2-yl]methanamine; 5-(Trifluoromethyl)-2-pyridylmethylamine; 2-Pyridinemethanamine, 5-(trifluoromethyl)-; α-Amino-5-(trifluoromethyl)-2-picoline; (5-Trifluoromethyl-pyridin-2-yl)-methylamine
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-2-Pyridinemethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.