Description

2,6-Di-o-Butyryl-Myo-Inositol 1,3,4,5-Tetrakisphosphate-Octakis(Acetoxymethyl) Ester is a highly specialized, cell-permeable derivative of inositol polyphosphate, designed for advanced biochemical and pharmacological research. This compound is critical for studying intracellular signaling pathways, particularly those involving inositol phosphates as second messengers. It is an essential tool for researchers and developers in pharmaceutical discovery, molecular biology, and cell signaling studies who require reliable, high-purity biochemical probes.

Application

• Biochemical Research: Used as a cell-permeable precursor for delivering myo-inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4) into living cells to study calcium signaling and other intracellular processes.
• Pharmaceutical Development: Serves as a key intermediate or tool compound in drug discovery programs targeting phosphoinositide signaling pathways, which are implicated in various diseases.
• Cell Biology Studies: Employed to investigate the role of specific inositol phosphates in cellular functions such as vesicle trafficking, gene expression, and apoptosis.
• Signal Transduction Research: Acts as a precise molecular tool to activate or inhibit specific nodes within the complex inositol phosphate signaling network.
• Neuroscience Research: Applied in studies of neuronal communication and plasticity where inositol phosphates play a critical regulatory role.

Basic Information

Item	Detail
Product Name	2,6-Di-o-Butyryl-Myo-Inositol 1,3,4,5-Tetrakisphosphate-Octakis(Acetoxymethyl) Ester
CAS No.	164199-43-3
Molecular Formula	C46H72O40P4
Molecular Weight	1369.0 g/mol (approx.)
Synonyms	Ins(1,3,4,5)P4-AM Ester; D-myo-Inositol 1,3,4,5-tetrakisphosphate, 2,6-di-O-butyryl-, octakis(acetoxymethyl) ester; Hexakis(acetoxymethyl) 2,6-di-O-butyryl-myo-inositol 1,3,4,5-tetrakisphosphate; Cell-permeable Ins(1,3,4,5)P4; IP4-AM Ester; Inositol tetrakisphosphate acetoxymethyl ester; caged Ins(1,3,4,5)P4 analog
EINECS	Contact for details

Quality Control

Every batch of 2,6-Di-o-Butyryl-Myo-Inositol 1,3,4,5-Tetrakisphosphate-Octakis(Acetoxymethyl) Ester is produced and analyzed under strict quality protocols to ensure the high purity and batch-to-batch consistency required for sensitive research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, NMR) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store desiccated under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.