Description

1-Bromo-3-(2,2,2-trifluoroethyl)benzene is a high-purity halogenated aromatic building block, distinguished by its bromine and trifluoroethyl substituents. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of both aryl bromide and fluorine-containing motifs. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoroethyl group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The aryl bromide moiety is reactive in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) for carbon-carbon bond formation.
• Fluorine Chemistry Research: An essential reagent for studying the effects of fluorine substitution on the physical and chemical properties of organic molecules.
• Polymer Modification: Incorporated as a monomer or modifier to introduce fluorine into polymer backbones, improving chemical resistance and thermal stability.

Basic Information

Product Name	1-Bromo-3-(2,2,2-Trifluoroethyl)Benzene
CAS No.	163975-05-1
Molecular Formula	C8H6BrF3
Molecular Weight	239.04 g/mol
Synonyms	3-Bromo-α,α,α-trifluoroethylbenzene; m-Bromo(trifluoroethyl)benzene; 1-Bromo-3-(2,2,2-trifluoroethyl)benzene; 3-(2,2,2-Trifluoroethyl)bromobenzene; (3-Bromophenyl)(trifluoro)methane; 3-Bromo-1-(2,2,2-trifluoroethyl)benzene; Benzene, 1-bromo-3-(2,2,2-trifluoroethyl)-
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(2,2,2-trifluoroethyl)benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.