Description

Fsh Receptor-Binding Inhibitor Fragment (Bi-10) CAS NO 163973-98-6 is a specialized peptide fragment designed to selectively inhibit the binding of Follicle-Stimulating Hormone (FSH) to its receptor. This compound is a critical research tool for studying reproductive endocrinology and developing novel therapeutic strategies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on fertility treatments, hormone-dependent disorders, and drug discovery programs.

Application

• Biochemical Research: Used as a reference standard and active probe in studies of FSH receptor (FSHR) signaling pathways and ligand-receptor interactions.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the design of novel non-peptide FSH receptor antagonists for therapeutic applications.
• Reproductive Biology Studies: Essential for in vitro and ex vivo experiments aimed at understanding folliculogenesis, spermatogenesis, and steroidogenesis.
• Assay Development: Employed in the development and validation of high-throughput screening (HTS) assays and competitive binding assays (e.g., ELISA, SPR) for FSHR activity.
• Mechanism of Action (MoA) Studies: Facilitates research into the structural basis of hormone-receptor binding and the development of resistance mechanisms.
• Academic & Clinical Research: Supports fundamental and translational research in endocrinology, oncology (for FSHR-expressing cancers), and metabolic disorders.

Basic Information

Product Name	Fsh Receptor-Binding Inhibitor Fragment (Bi-10)
CAS No.	163973-98-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	FSH Inhibitor Fragment Bi-10; Bi-10 Fragment; Follicle-Stimulating Hormone Receptor Antagonist Fragment; FSHR Binding Inhibitor Bi-10; Bi-10 Peptide; FSH Receptor Antagonist Bi-10; (4-Fluorobenzoyl)-D-Tyr-D-Phe-Lys-Lys-NH2 (related sequence); FSH Antagonist Analog
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Fsh Receptor-Binding Inhibitor Fragment (Bi-10) is characterized using advanced analytical techniques to confirm identity, purity, and biological activity. Certificates of Analysis (COA) detailing batch-specific results for purity (HPLC), mass spectrometry (MS), and other critical parameters are available upon request. We adhere to GMP-grade principles for handling and documentation to support preclinical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be kept under desiccated conditions upon opening. For long-term storage, consider storing under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity (Binding Assay)	Contact for details
Single Impurity (HPLC)	≤ 1.0%
Solubility	Soluble in DMSO, acetic acid; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.