Description

5-[3-(Trifluoromethyl)Phenyl]Pyridin-2-Amine is a high-value aromatic amine derivative featuring a trifluoromethylphenyl substituent, a structural motif of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to create compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drugs, particularly kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides that leverage the trifluoromethyl group for improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe Development: Employed in creating labeled compounds and molecular probes for target identification and validation in biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	5-[3-(Trifluoromethyl)Phenyl]Pyridin-2-Amine
CAS No.	163563-17-5
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	5-[3-(Trifluoromethyl)phenyl]pyridin-2-amine; 2-Amino-5-[3-(trifluoromethyl)phenyl]pyridine; 5-(3-Trifluoromethylphenyl)-2-pyridinamine; 5-(3-(Trifluoromethyl)phenyl)pyridin-2-amine; 5-(α,α,α-Trifluoro-m-tolyl)-2-aminopyridine; 2-Pyridinamine, 5-[3-(trifluoromethyl)phenyl]-; 163563-17-5
EINECS	Contact for details

Quality Control

Our 5-[3-(Trifluoromethyl)Phenyl]Pyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For projects requiring specific regulatory support, we can discuss cGMP or other relevant quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.