Description

3,4-Difluorobenzylsulfonyl Chloride is a high-purity, reactive organosulfur building block essential for advanced chemical synthesis. Its value lies in the sulfonyl chloride functional group, which enables efficient introduction of the sulfonyl moiety into target molecules, a critical step in developing compounds with specific biological or material properties. This intermediate is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the difluorobenzylsulfonyl group confers specific activity.
• Material Science Research: Serves as a precursor for creating specialized polymers, ligands, or functional materials that require sulfonyl linkages.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeling reagents for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	3,4-Difluorobenzylsulfonyl Chloride
CAS No.	163295-73-6
Molecular Formula	C7H5ClF2O2S
Molecular Weight	226.63 g/mol
Synonyms	3,4-Difluorophenylmethanesulfonyl chloride; (3,4-Difluorophenyl)methanesulfonyl chloride; 1-(Chlorosulfonyl)methyl-3,4-difluorobenzene; α-(Chlorosulfonyl)-3,4-difluorotoluene; Benzenemethanesulfonyl chloride, 3,4-difluoro-; 3,4-DFBSC
EINECS	Contact for details

Quality Control

Our 3,4-Difluorobenzylsulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopic methods, to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.