Description

6-Methyl-2-nitro-3-pyridyl trifluoromethanesulfonate is a high-purity triflate ester derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its excellent leaving group properties, enabling efficient nucleophilic substitution reactions to introduce the pyridyl moiety into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and fine chemicals requiring precise functionalization.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the substituted pyridine core is a critical pharmacophore.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized pyridine-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) with tailored properties.
• Cross-Coupling Reactions: An effective electrophile in Suzuki-Miyaura, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic methodologies.

Basic Information

Item	Details
Product Name	6-Methyl-2-nitro-3-pyridyl trifluoromethanesulfonate
CAS No.	163083-48-5
Molecular Formula	C8H7F3N2O5S
Molecular Weight	300.21 g/mol
Synonyms	2-Nitro-6-methylpyridin-3-yl trifluoromethanesulfonate; 3-Pyridinol, 6-methyl-2-nitro-, trifluoromethanesulfonate; 6-Methyl-2-nitro-3-pyridyl triflate; 3-Trifluoromethanesulfonyloxy-6-methyl-2-nitropyridine; Trifluoromethanesulfonic acid 6-methyl-2-nitro-3-pyridyl ester; 163083-48-5; 6-Methyl-2-nitro-3-pyridyl trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our production of 6-Methyl-2-nitro-3-pyridyl trifluoromethanesulfonate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.