Description

4-Difluoromethoxy-3-Methoxy-Benzaldehyde is a high-purity aromatic aldehyde building block of significant interest in advanced organic synthesis. Its unique difluoromethoxy and methoxy substitution pattern makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments engaged in the development of novel pharmaceuticals, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Used in the synthesis of fluorinated aromatic cores for advanced electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Ligand Preparation: Acts as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in custom synthesis and scale-up projects for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	4-Difluoromethoxy-3-Methoxy-Benzaldehyde
CAS No.	162401-70-9
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	3-Methoxy-4-(difluoromethoxy)benzaldehyde; 4-(Difluoromethoxy)-3-methoxybenzaldehyde; Benzaldehyde, 4-(difluoromethoxy)-3-methoxy-; Vanillin, 4-(difluoromethoxy)-; DFMB (abbreviation)
EINECS	Contact for details

Quality Control

Our production of 4-Difluoromethoxy-3-Methoxy-Benzaldehyde adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including GC, HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.