Description

2,3,4-Trifluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block essential for advanced organic synthesis. Its unique trifluorinated pattern on the benzene ring makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and electron-transport materials in organic light-emitting diodes (OLEDs) due to its influence on molecular polarity and packing.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or low surface energy properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl structures.
• Organic Synthesis Building Block: Employed in nucleophilic addition, reductive amination, and oxidation-reduction sequences to create a wide array of fluorinated benzyl alcohols, amines, and acids.

Basic Information

Product Name	2,3,4-Trifluorobenzaldehyde
CAS No.	161793-17-5
Molecular Formula	C7H3F3O
Molecular Weight	160.09 g/mol
Synonyms	2,3,4-Trifluorobenzenecarboxaldehyde; Benzaldehyde, 2,3,4-trifluoro-; 2,3,4-Trifluorobenzencarbaldehyde; 2,3,4-Trifluorophenylformaldehyde; α,2,3,4-Tetrafluorotoluene (obsolete); TFBA (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of our 2,3,4-Trifluorobenzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.