Description

2-Fluoro-4'-Hydroxy-3',4',5',6'-Tetrahydro-2'H[3,4']Bipyridinyl-1'-Carboxylic Acid is a high-purity fluorinated bipyridine derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Potential intermediate in the development of new-generation fluorinated pesticides and herbicides.
• Material Science Research: Investigated for the creation of specialized ligands in catalytic systems or functional materials.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up and cGMP production of clinical trial materials.

Basic Information

Product Name	2-Fluoro-4'-Hydroxy-3',4',5',6'-Tetrahydro-2'H[3,4']Bipyridinyl-1'-Carboxylic Acid
CAS No.	161610-13-5
Molecular Formula	C11H13FN2O3
Molecular Weight	240.23 g/mol
Synonyms	1'-Carboxy-2-fluoro-1,2,3,4-tetrahydro-4'-hydroxy-3,4'-bipyridine; 2-Fluoro-4'-hydroxy-3,4,5,6-tetrahydro-2'H-[3,4']bipyridinyl-1'-carboxylic acid; 2-Fluoro-4'-hydroxy-1,2,3,4-tetrahydro-[3,4']bipyridinyl-1'-carboxylic acid; 2-Fluoro-4'-hydroxy-3,4,5,6-tetrahydro-2H-[3,4'-bipyridine]-1'-carboxylic acid; 2-Fluoro-4'-hydroxy-3,4,5,6-tetrahydro-2'H-[3,4']bipyridinyl-1'-carboxylic acid; 2-Fluoro-4'-hydroxy-3,4,5,6-tetrahydro-2'H-[3,4']bipyridinyl-1'-carboxylic acid (CAS 161610-13-5)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4'-Hydroxy-3',4',5',6'-Tetrahydro-2'H[3,4']Bipyridinyl-1'-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes. We can support development and commercial projects requiring compliance with ICH guidelines and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.