Description

Chaetomellic Acid A Disodium Salt is a high-purity, synthetically derived salt form of a potent farnesyltransferase inhibitor. This compound is valued for its specific biochemical activity, making it a critical research tool for studying signal transduction pathways and cellular processes. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on oncology and metabolic disease research.

Application

• Biochemical Research: Used as a selective inhibitor of protein farnesyltransferase in enzymatic assays and mechanistic studies.
• Cell Biology Studies: Employed to investigate the role of Ras protein signaling pathways in cell proliferation, differentiation, and oncogenesis.
• Drug Discovery & Development: Serves as a reference standard and a lead compound in the development of novel anticancer therapeutics targeting prenylation.
• Academic Research: A key reagent for universities and research institutes exploring cancer biology, enzymology, and signal transduction.
• Pharmaceutical R&D: Utilized in high-throughput screening (HTS) and in vitro pharmacology to validate drug targets related to farnesyltransferase.

Basic Information

Product Name	Chaetomellic Acid A Disodium Salt
CAS No.	161308-35-6
Molecular Formula	C24H34Na2O6
Molecular Weight	464.51 g/mol
Synonyms	Disodium Chaetomellate A; Chaetomellic Acid A Sodium Salt; (2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienedioic Acid Disodium Salt; FTI-277 (related analog); Farnesyltransferase Inhibitor I (Disodium Salt); 2,6,10-Dodecatrienedioic acid, 3,7,11-trimethyl-, (2E,6E)-, disodium salt
EINECS	Contact for details

Quality Control

Our Chaetomellic Acid A Disodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccation and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.