Description

Ac-Leu-Val-Phe-Aldehyde is a specialized peptide aldehyde derivative, serving as a key intermediate and building block in advanced organic synthesis. This compound is valued for its role as a potent and selective inhibitor of proteolytic enzymes, particularly in biochemical research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in protease mechanism studies, inhibitor design, and the development of novel therapeutic agents.

Application

• Protease Inhibitor Research: Used as a selective, mechanism-based inhibitor for studying the function and structure of serine and cysteine proteases.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex peptide-based drug candidates targeting various diseases.
• Biochemical Assay Development: Employed in the design and validation of high-throughput screening assays to identify new enzyme inhibitors.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to optimize the potency and selectivity of protease-targeting compounds.
• Academic Research: A valuable tool in university and institutional labs for fundamental studies in enzymology and chemical biology.

Basic Information

Product Name	Ac-Leu-Val-Phe-Aldehyde
CAS No.	160369-84-6
Molecular Formula	C₂₃H₃₅N₃O₄
Molecular Weight	417.55 g/mol
Synonyms	Acetyl-Leu-Val-Phe-H; Ac-LVF-CHO; N-Acetyl-L-leucyl-L-valyl-L-phenylalaninal; Ac-Leu-Val-Phe-al; Protease Inhibitor Ac-LVF-CHO; Peptide Aldehyde Inhibitor; N-Acetyl-leucyl-valyl-phenylalaninal
EINECS	Contact for details

Quality Control

Our Ac-Leu-Val-Phe-Aldehyde is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.