Description

5-Isoxazol-3-Ylthiophene-2-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in modern organic synthesis. Its value lies in its dual heterocyclic structure, which enables the efficient construction of complex molecules with potential biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use as a key intermediate in medicinal chemistry and crop protection agent discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging its unique heterocyclic scaffold.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the synthesis of activity-based probes for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specialized sulfonamide or sulfonate functionalities.

Basic Information

Product Name	5-Isoxazol-3-Ylthiophene-2-Sulfonyl Chloride
CAS No.	160233-27-2
Molecular Formula	C7H4ClNO3S2
Molecular Weight	249.70 g/mol
Synonyms	3-(5-Chlorosulfonylthiophen-2-yl)isoxazole; 2-Thiophenesulfonyl chloride, 5-(3-isoxazolyl)-; 5-(Isoxazol-3-yl)thiophene-2-sulfonyl chloride; 5-(1,2-Oxazol-3-yl)thiophene-2-sulfonyl chloride; 3-(5-Chlorosulfonyl-2-thienyl)isoxazole; 5-(3-Isoxazolyl)-2-thiophenesulfonyl Chloride; Thiophene-2-sulfonyl chloride, 5-(3-isoxazolyl)-; 160233-27-2
EINECS	Contact for details

Quality Control

Every batch of 5-Isoxazol-3-Ylthiophene-2-Sulfonyl Chloride is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical synthesis work. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.