Description

5-Fluoro-2-Iodopyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a highly valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry for creating fluorinated and iodinated heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Cross-Coupling Reactions: Serves as an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the reactive iodine moiety.
• Ligand and Material Precursor: Utilized in the preparation of specialized ligands for catalysis and as a precursor for organic electronic materials.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic pathways and fluorination methodologies.

Basic Information

Product Name	5-Fluoro-2-Iodopyridine
CAS No.	159870-80-1
Molecular Formula	C5H3F1I1N1
Molecular Weight	222.99 g/mol
Synonyms	2-Iodo-5-fluoropyridine; 5-Fluoro-2-iodopyridine; 2-Iodo-5-fluoropyridine; Pyridine, 5-fluoro-2-iodo-; 5-Fluoropyridin-2-yl iodide; 159870-80-1; 5-Fluoro-2-iodo-pyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Iodopyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and industrial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.