Description

1-Bromo-4-(1-Fluoro-Ethyl)-Benzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on the benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry for introducing fluorinated and brominated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials used in displays and lighting technologies.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed reactions like Suzuki, Negishi, or Stille couplings to form biaryl structures.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) and the effects of fluorine substitution in organic molecules.
• Fine Chemical & Specialty Polymer Production: Employed in the synthesis of complex dyes, pigments, and specialty monomers for high-performance polymers.

Basic Information

Product Name	1-Bromo-4-(1-Fluoro-Ethyl)-Benzene
CAS No.	159298-87-0
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	1-Bromo-4-(1-fluoroethyl)benzene; 4-Bromo-α-fluoroethylbenzene; (1-Fluoroethyl)-4-bromobenzene; p-Bromo(1-fluoroethyl)benzene; 1-(4-Bromophenyl)-1-fluoroethane; α-Fluoro-4-bromoethylbenzene; 159298-87-0 (CAS)
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(1-Fluoro-Ethyl)-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reliable and consistent performance in sensitive synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Density	~1.45 g/cm³ (at 20°C)
Refractive Index	~1.52 (at 20°C)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.