Description

Quinoline-3-Sulfonyl Chloride CAS NO 159182-40-8 is a high-purity, reactive sulfonyl chloride derivative of quinoline, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the quinoline-3-sulfonyl moiety, enabling the creation of molecules with tailored properties for demanding applications. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Building block for synthesizing functional polymers, dyes, and photoactive compounds.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes and labeling reagents for proteomics and diagnostic research.
• Ligand and Catalyst Development: Precursor for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-molecule libraries.

Basic Information

Product Name	Quinoline-3-Sulfonyl Chloride
CAS No.	159182-40-8
Molecular Formula	C9H6ClNO2S
Molecular Weight	227.67 g/mol
Synonyms	3-Quinolinesulfonyl chloride; Quinoline-3-sulfonyl chloride; 3-Sulfonylchloroquinoline; Quinoline-3-sulfonic acid chloride; 159182-40-8; Quinoline-3-SO2Cl; 3-Quinolylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our Quinoline-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements in pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.