Description

Bace-1 CAS NO 158736-49-3 is a specialized chemical compound, specifically a β-secretase 1 (BACE-1) inhibitor, which plays a critical role in modulating enzymatic activity. This compound is of significant value in pharmaceutical research and development, particularly for its potential application in studying pathways associated with neurological conditions. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery, neuroscience research, and the development of therapeutic agents.

Application

• Pharmaceutical Research: A key tool compound for investigating β-secretase 1 (BACE-1) enzyme inhibition and its role in disease pathology.
• Drug Discovery & Development: Used as a reference standard or active pharmaceutical ingredient (API) intermediate in the development of novel therapeutic agents targeting Alzheimer's disease and related disorders.
• Neuroscience Studies: Employed in biochemical and cellular assays to study amyloid precursor protein (APP) processing and amyloid-beta peptide production.
• Biochemical Screening: Serves as a positive control or inhibitor in high-throughput screening (HTS) campaigns to identify new BACE-1 inhibitor leads.
• Academic Research: Utilized in university and institutional labs for fundamental research on protease enzymes and their inhibitors.
• Preclinical Studies: Applied in in vitro and in vivo models to evaluate the efficacy and pharmacokinetics of BACE-1 inhibition strategies.

Basic Information

Product Name	Bace-1
CAS No.	158736-49-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BACE-1 Inhibitor; β-Secretase 1 Inhibitor; (S)-tert-Butyl 1-oxo-1-(1-phenylethylamino)-3-(thiophen-2-yl)propan-2-ylcarbamate; BACE Inhibitor IV; CAS 158736-49-3; BACE1 Inhibitor; β-Secretase Inhibitor
EINECS	Contact for details

Quality Control

Our Bace-1 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including purity assay and identity confirmation. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.