Description

4-(Trifluoromethyl)Pyridine-3-Thiocarboxamide is a high-value trifluoromethylated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a pyridine core with a thiocarboxamide and a trifluoromethyl group, makes it an essential intermediate for developing novel active compounds. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to create new molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and material science applications.
• Fluorinated Compound Library: A valuable reagent for medicinal chemistry and combinatorial chemistry to expand fluorinated compound libraries for high-throughput screening.
• Chemical Biology Probes: Employed in the design and synthesis of chemical probes for studying biological pathways and protein functions.

Basic Information

Product Name	4-(Trifluoromethyl)Pyridine-3-Thiocarboxamide
CAS No.	158063-54-8
Molecular Formula	C7H5F3N2S
Molecular Weight	206.19 g/mol
Synonyms	3-Pyridinecarbothioamide, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)nicotinothioamide; 4-Trifluoromethylpyridine-3-thiocarboxamide; 4-(Trifluoromethyl)-3-pyridinylcarbothioamide; 4-(Trifluoromethyl)-3-pyridinecarbothioamide; 4-Trifluoromethyl-3-pyridinecarbothioamide; 4-(Trifluoromethyl)pyridine-3-carbothioamide
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Pyridine-3-Thiocarboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.