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15(S)-15-Methyl Prostaglandin F2α Isopropyl Ester CAS NO 157283-72-2


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CAS No.:157283-72-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

15(S)-15-Methyl Prostaglandin F2α Isopropyl Ester is a synthetic analog of prostaglandin F2α, a potent bioactive lipid mediator. This compound is valued for its enhanced metabolic stability and targeted biological activity compared to its natural counterpart. It is primarily utilized in advanced pharmaceutical research and development, particularly in the fields of ophthalmology and reproductive medicine, serving as a critical intermediate or active pharmaceutical ingredient (API).

Application

  • Pharmaceutical Intermediate: A key synthetic building block for the production of prostaglandin-based therapeutics.
  • Ophthalmic Drug Development: Used in research for glaucoma treatments due to its intraocular pressure-lowering effects.
  • Reproductive Health Research: Investigated for applications in labor induction and the management of postpartum hemorrhage.
  • Biochemical Research: Serves as a standard or probe in studies involving FP prostanoid receptor signaling pathways.
  • Veterinary Medicine: Potential use in animal health for estrus synchronization and parturition management.

Basic Information

Product Name 15(S)-15-Methyl Prostaglandin F2α Isopropyl Ester
CAS No. 157283-72-2
Molecular Formula C24H40O5
Molecular Weight 408.58 g/mol
Synonyms 15(S)-15-Methyl-PGF2α isopropyl ester; Travoprost Impurity C; 15-Methylprostaglandin F2α isopropyl ester; 9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid isopropyl ester; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid 1-methylethyl ester; AL-5848; AL 5848; Bimatoprost related compound B
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Quality Control

Our 15(S)-15-Methyl Prostaglandin F2α Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the sealed vial under an inert atmosphere (e.g., argon or nitrogen) at -20°C or below to minimize oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (IR) Conforms to reference spectrum
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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