Description

2-Methoxy-4-Fluorobenzyl Chloride is a versatile fluorinated benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive benzylic chloride group and substituted aromatic ring, enabling the introduction of the 2-methoxy-4-fluorobenzyl moiety into target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require fluorinated aromatic structures.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a precursor to other functional groups like alcohols or amines.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating novel chemical entities in R&D laboratories.

Basic Information

Product Name	2-Methoxy-4-Fluorobenzyl Chloride
CAS No.	157068-04-7
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	1-(Chloromethyl)-2-methoxy-4-fluorobenzene; 4-Fluoro-2-methoxybenzyl chloride; (4-Fluoro-2-methoxyphenyl)methyl chloride; 2-Methoxy-4-fluorobenzylchloride; α-Chloro-2-methoxy-4-fluorotoluene; 4-Fluoro-o-anisyl chloride; 2-Methoxy-4-fluorophenylmethyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-Fluorobenzyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.