Description

2,5-Dibromo-3-Fluoropyridine is a halogenated pyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. This compound is valued for its ability to introduce both bromine and fluorine substituents into target molecules, enabling precise structural modifications. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic electronic materials, such as semiconductors and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of bromine atoms.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	2,5-Dibromo-3-Fluoropyridine
CAS No.	156772-60-0
Molecular Formula	C5H2Br2FN
Molecular Weight	254.88 g/mol
Synonyms	3-Fluoro-2,5-dibromopyridine; 2,5-Dibromo-3-fluoropyridine; Pyridine, 2,5-dibromo-3-fluoro-; 3-Fluoro-2,5-dibromopyridine; 2,5-Dibromo-3-fluoro-pyridine
EINECS	Contact for details

Quality Control

Our 2,5-Dibromo-3-Fluoropyridine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.