Description

Bg Iii Toxin CAS NO 156680-12-5 is a specialized biochemical compound, also known as Brevetoxin B, which is a potent marine neurotoxin produced by the dinoflagellate *Karenia brevis*. This compound is of significant interest for its specific mechanism of action on voltage-gated sodium channels. It serves as a critical reference standard and research tool for scientists in toxicology, pharmacology, and environmental monitoring. Key industries and research institutions rely on this high-purity material for analytical method development, toxicological studies, and the calibration of detection equipment.

Application

• Reference Standard for Analytical Testing: Primary use as a certified reference material (CRM) in HPLC, LC-MS, and other analytical techniques for the quantification of marine toxins in seafood and water samples.
• Neuroscience and Pharmacology Research: Tool for studying the structure and function of voltage-gated sodium channels, neuronal excitability, and the pathophysiology of neurotoxic shellfish poisoning (NSP).
• Environmental Monitoring and Public Health: Calibration standard for assays and kits used to monitor algal blooms (red tides) and ensure shellfish safety for human consumption.
• Toxicological Studies: Used in in vitro and in vivo research to investigate the effects, metabolism, and potential treatments for brevetoxin exposure.
• Method Development and Validation: Essential for laboratories developing, optimizing, and validating regulatory-compliant testing methods for marine biotoxins.
• Educational and Diagnostic Purposes: Used in academic settings and by diagnostic manufacturers to create training materials and quality control reagents.

Basic Information

Product Name	Bg Iii Toxin
CAS No.	156680-12-5
Molecular Formula	C50H70O14
Molecular Weight	894.5 g/mol
Synonyms	Brevetoxin B; Brevetoxin-2; PbTx-2; GB-2; BTX-B; *Karenia brevis* Toxin B; Marine Neurotoxin B; (2S,3S,4R,5S,7R,9R,10S,11R,12S,14R,16S,18S,20S,23R,25R,27S,29S,31S,33R,35R,37S,39R,41S,43S,44R,46S)-23,44-Diacetyloxy-39-(acetyloxymethyl-46-ethyl-3,5,7,10,12,14,16,18,20,25,27,29,31,33,35,37,39,41,43,46-icosahydroxy-4,11-dimethyl-2-propan-2-yl-1,6,8,15,17,19,21,24,26,28,30,32,34,36,38,40,42,45-octadecaoxanonacyclo[23.22.0.02,7.03,44.05,43.09,37.010,35.012,33.014,31.016,29.018,27.020,25]heptatetracontane-13,47-dione
EINECS	Contact for details

Quality Control

Every batch of Bg Iii Toxin (CAS 156680-12-5) is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and stability testing to ensure they meet the exacting standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, purity, and identification. We support compliance with relevant guidelines for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.