Description

7-o-(Galactosyl)Brefeldin A is a glycosylated derivative of the well-known fungal metabolite Brefeldin A, offering enhanced solubility and targeted biological activity. This specialized compound is valued for its role as a potent and selective inhibitor of protein transport from the endoplasmic reticulum to the Golgi apparatus. It is primarily utilized by researchers in pharmaceutical development, biochemistry, and cell biology for studying intracellular trafficking mechanisms and as a lead compound in drug discovery programs.

Application

• Biochemical Research: A critical tool for studying vesicular transport, Golgi apparatus function, and protein secretion pathways in eukaryotic cells.
• Pharmaceutical R&D: Serves as a key reference standard and a structural scaffold for developing novel therapeutics targeting intracellular transport disorders.
• Cell Biology Studies: Used to induce the rapid redistribution of Golgi proteins into the endoplasmic reticulum, facilitating studies on organelle dynamics.
• Mechanism of Action (MOA) Studies: Employed to elucidate the specific molecular pathways affected by glycosylation on bioactive natural products.
• High-Throughput Screening (HTS): Utilized as a control compound in assays designed to discover new inhibitors of secretory pathways.

Basic Information

Product Name	7-o-(Galactosyl)Brefeldin A
CAS No.	156663-50-2
Molecular Formula	C28H40O10
Molecular Weight	536.62 g/mol
Synonyms	7-O-Galactosyl Brefeldin A; Brefeldin A 7-O-β-D-galactopyranoside; Galactosyl Brefeldin A; 7-O-(β-D-Galactopyranosyl)brefeldin A; BFA-galactoside; (1R,2E,6S,10E,11aS,13S,14aR)-1,6,13-Trihydroxy-3,7,11-trimethyl-14-oxo-1,2,6,7,8,9,10,11,11a,12,13,14a-dodecahydrocyclopenta[a]cyclopropa[f]cycloundecen-4-yl β-D-galactopyranoside
EINECS	Contact for details

Quality Control

Our 7-o-(Galactosyl)Brefeldin A is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring reliable performance in sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed under an inert atmosphere after each use to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.