Description

Altumomab is a monoclonal antibody-based radiopharmaceutical agent, identified by CAS NO 156586-92-4. This compound is specifically engineered for targeted diagnostic and therapeutic applications in oncology, offering high specificity for tumor-associated antigens. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development of advanced cancer diagnostics and radioimmunotherapy treatments.

Application

• Radioimmunotherapy (RIT): As a carrier for radioactive isotopes (e.g., Iodine-131, Yttrium-90) for targeted cancer treatment.
• Diagnostic Imaging: Conjugated with radionuclides like Technetium-99m for tumor detection and staging via SPECT or gamma camera imaging.
• Clinical Research: Used in preclinical and clinical trials to study tumor targeting, pharmacokinetics, and biodistribution.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the formulation of novel oncological therapeutics.
• Biomarker Studies: Employed in immunohistochemistry and in vitro assays to identify and validate specific cancer cell surface markers.

Basic Information

Product Name	Altumomab
CAS No.	156586-92-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Altumomab; Anti-CEA Monoclonal Antibody BW 431/26; BW-431/26; BW 431/26; CEA-Scan; Arcitumomab; Technetium Tc 99m Arcitumomab; IMMU-4; Monoclonal Antibody BW 431/26
EINECS	Contact for details

Quality Control

Our Altumomab is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC, sterility testing, endotoxin analysis, and immunoreactivity assays to ensure it meets the stringent requirements for pharmaceutical and research use. Certificates of Analysis (COA) documenting compliance with relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under controlled humidity conditions to maintain stability. For long-term storage, consider aliquoting and freezing at -20°C or below under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/Immunoassay)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Protein Content (UV)	As per COA
Immunoreactivity	≥ 80%
Sterility (Membrane Filtration)	Sterile
Endotoxin (LAL)	< 10 EU/mg
pH	6.5 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.