Description

.Beta.-D-Glucopyranoside, 1,2,7-Tris(Acetyloxy)Hexahydro-1H-Pyrrolizin-3-Ylmethyl, 2,3,4,6-Tetraacetate, 1R-(1.Alpha.,2.Beta.,3.Alpha.,7.Beta.,7A.Alpha.)- is a complex, high-purity synthetic intermediate with a defined stereochemistry, identified by CAS No. 156205-65-1. This compound is of significant value for its role as a key building block in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs), especially those with glycosidic or pyrrolizidine alkaloid-related structures.
• Biochemical Research: Used as a substrate or reference standard in enzymatic studies and metabolic pathway research.
• Glycoscience Development: Serves as a protected glycosyl donor or acceptor for the synthesis of novel carbohydrates and glycoconjugates.
• Agrochemical Synthesis: Employed in the research and development of advanced crop protection agents with specific biological activity.
• Process Chemistry: Utilized for route scouting and optimization in multi-step synthetic sequences requiring high stereochemical fidelity.

Basic Information

Product Name	.Beta.-D-Glucopyranoside, 1,2,7-Tris(Acetyloxy)Hexahydro-1H-Pyrrolizin-3-Ylmethyl, 2,3,4,6-Tetraacetate, 1R-(1.Alpha.,2.Beta.,3.Alpha.,7.Beta.,7A.Alpha.)-
CAS No.	156205-65-1
Molecular Formula	C28H39NO15
Molecular Weight	629.61 g/mol
Synonyms	1R-(1α,2β,3α,7β,7aα)-1,2,7-Tris(acetyloxy)hexahydro-1H-pyrrolizin-3-ylmethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside; (1R,2R,3R,7S,7aR)-1,2,7-Tris(acetoxy)octahydro-1H-pyrrolizin-3-ylmethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside; β-D-Glucopyranoside, 1,2,7-tris(acetyloxy)hexahydro-1H-pyrrolizin-3-ylmethyl 2,3,4,6-tetraacetate, (1R,2R,3R,7S,7aR)-; Triptolide derivative intermediate; PG490 derivative intermediate.
EINECS	Contact for details

Quality Control

Our .Beta.-D-Glucopyranoside, 1,2,7-Tris(Acetyloxy)Hexahydro-1H-Pyrrolizin-3-Ylmethyl, 2,3,4,6-Tetraacetate, 1R-(1.Alpha.,2.Beta.,3.Alpha.,7.Beta.,7A.Alpha.)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is -20°C or below. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.