Description

Cyclosporin A-Derivative 2 CAS NO 156047-45-9 is a chemically modified analog of the potent immunosuppressive agent Cyclosporin A, designed to explore refined pharmacological profiles. This derivative is of significant interest for advanced research and development in immunology and transplant medicine, offering a pathway to novel therapeutic agents with potentially improved efficacy or reduced side effects. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing next-generation immunosuppressive and anti-inflammatory drugs.

Application

• Immunosuppressive Research: Serves as a key intermediate or reference standard in the development of new immunosuppressive therapies for organ transplantation and autoimmune diseases.
• Structure-Activity Relationship (SAR) Studies: Used to investigate the correlation between chemical structure modifications of Cyclosporin A and their biological activity.
• Pharmacological Profiling: Employed in in vitro and in vivo studies to assess potency, selectivity, and metabolic stability compared to the parent compound.
• Biochemical Assay Development: Acts as a tool compound in high-throughput screening assays to identify and validate new targets in immunomodulatory pathways.
• Process Chemistry & API Development: Used as a building block or intermediate in the synthetic route for novel active pharmaceutical ingredients (APIs).
• Reference Standard: Provides a characterized compound for quality control and analytical method development in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	Cyclosporin A-Derivative 2
CAS No.	156047-45-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclosporin A Analog 2; Cyclosporine A Derivative 2; CsA-Derivative 2; [D-Ser]⁸-Cyclosporin A (example based on common modifications); Cyclosporin Derivative (156047-45-9); Immunosuppressant Cyclosporin Analog; Cyclosporin A Modification 2
EINECS	Contact for details

Quality Control

Our Cyclosporin A-Derivative 2 is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and development purposes. A Certificate of Analysis (COA) detailing specific results for purity, identity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.