Description

1-(Methoxymethyl)-4-(Trifluoromethyl)Benzene is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a methoxymethyl ether and a trifluoromethyl group, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those requiring the metabolic stability and lipophilicity imparted by the trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter surface properties, chemical resistance, or optical characteristics.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki or Sonogashira couplings, to introduce the (trifluoromethyl)benzene moiety into more complex structures.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new reactions and material properties involving fluorinated aromatics.

Basic Information

Product Name	1-(Methoxymethyl)-4-(Trifluoromethyl)Benzene
CAS No.	155820-05-6
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	α-Methoxy-4-(trifluoromethyl)toluene; 4-(Trifluoromethyl)benzyl methyl ether; (4-(Trifluoromethyl)phenyl)methoxymethane; 1-Methoxymethyl-4-trifluoromethylbenzene; p-(Trifluoromethyl)benzyl Methyl Ether; 4-(Methoxymethyl)benzotrifluoride; Benzene, 1-(methoxymethyl)-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-(Methoxymethyl)-4-(Trifluoromethyl)Benzene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.460
Density (20°C)	1.20 - 1.30 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.