Description

2-Amino-3,5-Dimethylimidazo(4,5-B)Pyridine is a heterocyclic aromatic amine of significant interest in advanced chemical research and development. This compound matters as a key synthetic intermediate and reference standard for the study of mutagenic and carcinogenic substances. It is primarily needed by research institutions, analytical laboratories, and pharmaceutical developers working in toxicology, food safety, and environmental health. The chemical structure makes it a critical compound for understanding the formation and effects of heterocyclic amines (HCAs).

Application

• Analytical Reference Standard: Used as a certified standard in HPLC, LC-MS, and GC-MS for the quantification of heterocyclic aromatic amines (HAAs) in complex matrices.
• Toxicological Research: Serves as a model compound in studies investigating the mutagenicity, genotoxicity, and metabolic pathways of cooked food mutagens.
• Food Safety Analysis: Critical for developing and validating analytical methods to detect and quantify harmful amines in processed meats, grilled foods, and other thermally treated protein-rich products.
• Biomarker Studies: Employed in research to identify and understand DNA adducts formed by heterocyclic amines, aiding in exposure and risk assessment.
• Pharmaceutical Impurity Profiling: Used in method development for detecting and controlling potentially genotoxic impurities (PGIs) in active pharmaceutical ingredients (APIs).
• Environmental Monitoring: Applied in research to trace the environmental fate and transport of heterocyclic amines from various sources.
• Chemical Synthesis Intermediate: Acts as a specialized building block for synthesizing more complex molecules for research purposes.

Basic Information

Item	Detail
Product Name	2-Amino-3,5-Dimethylimidazo(4,5-B)Pyridine
CAS No.	155789-83-6
Molecular Formula	C8H10N4
Molecular Weight	162.19 g/mol
Synonyms	2-Amino-3,5-dimethylimidazo[4,5-b]pyridine; 3,5-Dimethyl-2-aminoimidazo[4,5-b]pyridine; 3,5-DiMeIQ; 3,5-Dimethyl-2-aminopyrido[4',5':4,5]imidazole; 3,5-Dimethyl-2-amino-3H-imidazo[4,5-b]pyridine; 3,5-Dimethyl-2-amino-1H-imidazo[4,5-b]pyridine; 3,5-Dimethyl-2-amino-1H-pyrido[4,5-b]imidazole; 3,5-Dimethyl-2-amino-1H-pyrido[4',5':4,5]imidazole
EINECS	Contact for details

Quality Control

Our 2-Amino-3,5-Dimethylimidazo(4,5-B)Pyridine is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC purity analysis and structural confirmation (NMR, MS), to ensure identity, potency, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems support research requiring traceable and reliable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.