Description

Okadaic Acid Ammonium Salt is a high-purity, cell-permeable biochemical tool compound widely used in biomedical research. This potent and selective inhibitor of protein phosphatases PP1 and PP2A is critical for studying cellular signaling pathways, phosphorylation events, and tumor promotion. It is an essential reagent for researchers in pharmaceutical development, toxicology, and molecular biology who require reliable, well-characterized compounds for their experimental models.

Application

• Biomedical Research: A key tool for studying signal transduction, cell cycle regulation, and apoptosis by inhibiting serine/threonine protein phosphatases.
• Toxicology Studies: Used as a reference standard in the study of diarrhetic shellfish poisoning (DSP) and to investigate the mechanisms of marine biotoxins.
• Cancer Research: Employed to model tumor promotion and investigate the role of protein phosphorylation in oncogenesis and metastasis.
• Neuroscience: Applied in research on synaptic plasticity, memory formation, and neurodegenerative disease pathways.
• Biochemical Assay Development: Serves as a critical control and standard in phosphatase activity assays and high-throughput screening (HTS) platforms.
• Academic & Pharmaceutical R&D: Essential for basic research and drug discovery programs targeting phosphatase-related diseases.

Basic Information

Item	Details
Product Name	Okadaic Acid Ammonium Salt
CAS No.	155716-06-6
Molecular Formula	C44H68NO13 • xNH3
Molecular Weight	Contact for details
Synonyms	Okadaic Acid Ammonium; Ammonium Okadaate; 9,10-Deepithio-9,10-didehydroacanthifolicin Ammonium Salt; PP1/PP2A Inhibitor; OA Ammonium Salt; DSP Toxin Standard; NSC 153858 (Ammonium Salt); 1H-Benz[cd]indole-2-carboxylic Acid Derivative Ammonium Salt
EINECS	Contact for details

Quality Control

Every batch of Okadaic Acid Ammonium Salt is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with high-purity standards. Certificates of Analysis (COA) with detailed chromatograms and analytical data are available upon request to support your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥95% (Area %)
Purity (HPLC)	≥98%
Water Content (KF)	≤5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.