Description

Ethanone, 2-Fluoro-1-(3-Pyridinyl)- (9Ci) CAS NO 155557-12-3 is a high-purity fluorinated pyridinyl ketone building block, valued for its role in introducing specific fluorine-substituted motifs into complex molecular architectures. This compound is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its unique structure enables precise modulation of biological activity and physicochemical properties. It is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical research and development sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors and liquid crystal materials.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes used in diagnostic assays.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	Ethanone, 2-Fluoro-1-(3-Pyridinyl)- (9Ci)
CAS No.	155557-12-3
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	2-Fluoro-1-(pyridin-3-yl)ethanone; 3-Acetylpyridine, 2-fluoro-; 1-(3-Pyridinyl)-2-fluoroethanone; 2-Fluoro-1-(3-pyridinyl)ethanone; 2-Fluoro-3-acetylpyridine; 3-(2-Fluoroacetyl)pyridine; 2-Fluoro-1-(3-pyridyl)ethanone; α-Fluoro-3-pyridyl methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Fluoro-1-(3-Pyridinyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in cGMP (current Good Manufacturing Practice) environments and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.