Description

n-Butyldeoxymannojirimycinhcl is a high-purity, synthetic iminosugar derivative used as a potent and selective glycosidase inhibitor. This compound is critical for biochemical research and pharmaceutical development, particularly in the study of glycoprotein processing and metabolic disorders. It is primarily utilized by researchers and manufacturers in the life sciences, biotechnology, and pharmaceutical industries for drug discovery and mechanism-of-action studies.

Application

• Biochemical Research: As a selective inhibitor of α-mannosidase enzymes for studying N-linked glycan processing and endoplasmic reticulum-associated degradation (ERAD).
• Pharmaceutical Development: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of therapeutics for lysosomal storage diseases and viral infections.
• Cell Biology Studies: Used to induce the misfolding of glycoproteins in cell culture models to study diseases like cystic fibrosis and certain forms of cancer.
• Antiviral Research: Investigated for its potential to inhibit the replication of enveloped viruses, such as hepatitis B and C, by disrupting viral glycoprotein maturation.
• Metabolic Pathway Analysis: A tool compound for probing the calnexin/calreticulin cycle and quality control mechanisms within the secretory pathway.

Basic Information

Product Name	n-Butyldeoxymannojirimycinhcl
CAS No.	155501-85-2
Molecular Formula	C14H28N2O4 • HCl
Molecular Weight	324.85 g/mol (for free base: 288.38)
Synonyms	N-Butyl-deoxymannojirimycin hydrochloride; Deoxymannojirimycin, N-butyl-, hydrochloride; 1,5-Dideoxy-1,5-imino-N-butyl-D-mannitol hydrochloride; Bu-DMJ; α-Mannosidase inhibitor II; MDL 28,574; SC-48334
EINECS	Contact for details

Quality Control

Our n-Butyldeoxymannojirimycinhcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.