Description

Cck-B Receptor Antagonist 2 CAS NO 155412-88-7 is a potent and selective small molecule inhibitor of the cholecystokinin B (CCK-B) receptor. This compound is a critical research tool for investigating the role of CCK-B receptors in central nervous system and gastrointestinal functions. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on neuropharmacology, anxiety, pain management, and digestive disorder research.

Application

• Pharmacological Research: Used as a standard reference compound in in vitro and in vivo studies to elucidate the physiological and pathological roles of CCK-B receptors.
• Drug Discovery & Development: Serves as a lead compound or benchmark for developing novel therapeutics targeting anxiety, panic disorders, and neuropathic pain.
• Neuroscience Studies: Essential for exploring the modulation of neurotransmitter release, neuronal excitability, and behaviors associated with the CCKergic system.
• Gastrointestinal Research: Applied in studies investigating gastric acid secretion, pancreatic enzyme release, and gut motility mediated by CCK-B receptors.
• Biochemical Assay Development: Used to validate and calibrate high-throughput screening (HTS) assays for receptor binding and functional activity.
• Academic & Clinical Research: Supports fundamental research into the molecular mechanisms of satiety, nociception, and dopamine-mediated behaviors.

Basic Information

Product Name	Cck-B Receptor Antagonist 2
CAS No.	155412-88-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CCK-B Antagonist 2; PD-134308; CI-988; (R)-4-[2-[3-(1H-Indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic acid; PD 134308; CI 988; Gastrin Receptor Antagonist PD-134308
EINECS	Contact for details

Quality Control

Our Cck-B Receptor Antagonist 2 is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Our quality commitment supports reproducible and reliable experimental results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.