Description

6-Trifluoromethyl-Pyridine-2-Carboxylic Acid Methyl Ester is a high-value fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its trifluoromethyl group and ester functionality make it a versatile intermediate for creating compounds with enhanced metabolic stability, lipophilicity, and bioavailability. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and other functional materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Trifluoromethyl-Pyridine-2-Carboxylic Acid Methyl Ester
CAS No.	155377-05-2
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	Methyl 6-(trifluoromethyl)pyridine-2-carboxylate; Methyl 6-(trifluoromethyl)picolinate; 2-Pyridinecarboxylic acid, 6-(trifluoromethyl)-, methyl ester; 6-(Trifluoromethyl)picolinic acid methyl ester; 6-Trifluoromethyl-2-picolinic acid methyl ester; Methyl 6-trifluoromethylpicolinate; 155377-05-2
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-Pyridine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.