Description

Bimatoprost CAS NO 155206-00-1 is a synthetic prostaglandin analog, a high-purity active pharmaceutical ingredient (API) of significant commercial and therapeutic importance. This compound is valued for its potent pharmacological activity, primarily as a selective prostaglandin receptor agonist. It is an essential raw material for pharmaceutical manufacturers developing ophthalmic solutions and other advanced therapeutic formulations. Industries requiring high-grade prostaglandin derivatives for research, development, and commercial production rely on a consistent supply of this critical API.

Application

• Primary Pharmaceutical Ingredient: The key API in prescription ophthalmic solutions for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
• Cosmetic Dermatology Formulations: Used in topical solutions and serums for the treatment of hypotrichosis of the eyelashes, promoting growth, thickness, and darkness.
• Pharmaceutical Research & Development (R&D): Serves as a critical reference standard and building block in preclinical and clinical studies exploring new prostaglandin-based therapies.
• Advanced Drug Delivery Systems: Incorporated into novel delivery platforms such as implants, sustained-release formulations, and combination products.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of finished dosage forms under cGMP.
• Analytical Standard: Utilized as a high-purity standard in quality control laboratories for HPLC, LC-MS, and other analytical method development and validation.

Basic Information

Product Name	Bimatoprost
CAS No.	155206-00-1
Molecular Formula	C25H37NO4
Molecular Weight	415.57 g/mol
Synonyms	7-[3,5-Dihydroxy-2-[3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-N-ethylheptenamide; AGN 192024; Bimatoprostum; Lumigan (brand name active ingredient); Prostaglandin F2α ethylamide; 17-Phenyl-trinor-PGF2α ethyl amide; (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-N-ethylhept-5-enamide
EINECS	Contact for details

Quality Control

Our Bimatoprost is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for assay, related substances, residual solvents, and other critical parameters. We support compliance with major pharmacopoeial standards, and our quality commitment is designed to meet the needs of cGMP manufacturing for global pharmaceutical markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 1.0%
Water (KF)	NMT 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.