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4-((2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridin-3-Yl)Methyl)-5-Propyl-[1,1-Biphenyl]-2-Sulfonamide CAS NO 154553-71-6


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CAS No.:154553-71-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-((2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridin-3-Yl)Methyl)-5-Propyl-[1,1-Biphenyl]-2-Sulfonamide is a high-purity, complex heterocyclic sulfonamide compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting innovative drug discovery programs.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
  • Biochemical Research: Used as a reference standard or probe molecule in enzymatic and receptor binding assays to study biological pathways.
  • Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
  • API Development: Employed in process chemistry for the scale-up and production of active pharmaceutical ingredients under GMP conditions.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
  • Academic Research: Utilized in university and institutional labs for cutting-edge chemical biology and drug discovery research.

Basic Information

Product Name 4-((2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridin-3-Yl)Methyl)-5-Propyl-[1,1-Biphenyl]-2-Sulfonamide
CAS No. 154553-71-6
Molecular Formula C28H30N4O2S
Molecular Weight 486.63 g/mol
Synonyms 4-[(2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]-5-propyl-1,1'-biphenyl-2-sulfonamide; 5-Propyl-4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)biphenyl-2-sulfonamide; Biphenyl-2-sulfonamide, 4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)-5-propyl-; CAS 154553-71-6; 154553-71-6; 4-[(2-Ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-5-propylbiphenyl-2-sulfonamide
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Quality Control

Our 4-((2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridin-3-Yl)Methyl)-5-Propyl-[1,1-Biphenyl]-2-Sulfonamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with quality standards suitable for GMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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