Description

Cyclopropane, 1,1-Difluoro-2,3-Dipropyl-, trans- (9Ci) is a specialized fluorinated cyclopropane derivative, a class of compounds valued for their unique structural and electronic properties. This compound serves as a high-value building block in advanced organic synthesis, particularly for introducing the rigid, lipophilic cyclopropane motif with fluorine substitution. It is primarily utilized by pharmaceutical and agrochemical research organizations engaged in the development of novel active ingredients, where its distinct stereochemistry and fluorination pattern are critical for modulating biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for introducing fluorinated cyclopropane scaffolds known to enhance potency and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorinated cyclopropane structure can contribute to improved efficacy and environmental profile.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials that require specific fluorine-containing motifs for tailored surface properties or stability.
• Ligand and Catalyst Development: Acts as a precursor or a functional component in the design of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Fluorine Chemistry Studies: Serves as a model compound in academic and industrial research focused on the reactivity and applications of fluorinated small rings.

Basic Information

Product Name	Cyclopropane, 1,1-Difluoro-2,3-Dipropyl-, trans- (9Ci)
CAS No.	154413-35-1
Molecular Formula	C9H16F2
Molecular Weight	162.22 g/mol
Synonyms	trans-1,1-Difluoro-2,3-dipropylcyclopropane; 1,1-Difluoro-2,3-dipropylcyclopropane, trans-; NSC 405124; (1R,2S)-1,1-Difluoro-2,3-dipropylcyclopropane; (1S,2R)-1,1-Difluoro-2,3-dipropylcyclopropane; trans-2,3-Dipropyl-1,1-difluorocyclopropane
EINECS	Contact for details

Quality Control

Our high-purity fluorinated intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including GC, HPLC, NMR, and MS, to confirm identity, isomeric purity, and chemical composition. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (GC)	≥ 98.0% trans-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.