Description

5-(4-Fluorophenyl)Pyridine-3-Carbonitrile is a high-value fluorinated pyridine derivative, a key heterocyclic building block prized for its unique electronic and steric properties. Its core value lies in enabling the synthesis of complex molecules with tailored biological activity and material characteristics. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to innovate new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and other functional materials requiring fluorinated aromatic systems.
• Chemical Biology Probes: Acts as a building block for fluorescent tags, photoaffinity labels, and other molecular probes used in diagnostic and research applications.

Basic Information

Product Name	5-(4-Fluorophenyl)Pyridine-3-Carbonitrile
CAS No.	154237-18-0
Molecular Formula	C12H7FN2
Molecular Weight	198.20 g/mol
Synonyms	3-Cyano-5-(4-fluorophenyl)pyridine; 5-(4-Fluorophenyl)-3-pyridinecarbonitrile; 5-(p-Fluorophenyl)nicotinonitrile; 3-Pyridinecarbonitrile, 5-(4-fluorophenyl)-; 154237-18-0; 5-(4-Fluorophenyl)nicotinonitrile
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.