Description

Dinoprostone CAS NO 154170-57-7 is a high-purity prostaglandin E2 (PGE2) analog, a critical bioactive compound used in advanced pharmaceutical applications. Its primary value lies in its potent biological activity, specifically as a uterine stimulant and cervical ripening agent, making it essential for ensuring product efficacy and batch-to-batch consistency in drug manufacturing. This compound is vital for pharmaceutical R&D laboratories and manufacturers developing and producing specialized obstetric, gynecological, and other therapeutic formulations.

Application

• Pharmaceutical Active Ingredient: Core active pharmaceutical ingredient (API) in formulations for cervical ripening and labor induction.
• Obstetric & Gynecological Therapeutics: Used in the development and production of drugs for managing postpartum hemorrhage and facilitating medical termination of pregnancy.
• Biochemical Research: Serves as a key reference standard and reagent in prostaglandin pathway research, receptor binding studies, and cell signaling experiments.
• Drug Delivery System Development: Incorporated into the research of controlled-release formulations, such as vaginal inserts and gels, to optimize pharmacokinetic profiles.
• Quality Control & Analytical Testing: Employed as a certified reference material (CRM) for assay calibration, method validation, and impurity profiling in QC laboratories.

Basic Information

Product Name	Dinoprostone
CAS No.	154170-57-7
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	Prostaglandin E2; PGE2; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; Prostin E2; Cerviprost; Propess; Prepidil; Dinoprostona
EINECS	Contact for details

Quality Control

Our Dinoprostone is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates and reference standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can support compliance with cGMP standards for pharmaceutical ingredient supply upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled temperature of 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.