Description

Ethyl Docetaxel is a semi-synthetic derivative of paclitaxel, designed to offer enhanced pharmacological properties. This compound is a critical intermediate in the synthesis of Docetaxel, a cornerstone chemotherapeutic agent used globally. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in oncology drug development and production.

Application

• Pharmaceutical Intermediate: Key precursor in the commercial synthesis of the anticancer drug Docetaxel.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships of taxane derivatives.
• Process Development: Employed in the optimization and scaling of Docetaxel manufacturing processes within GMP facilities.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions.
• Analog Synthesis: A starting material for the research and development of novel taxane-based therapeutic agents.

Basic Information

Product Name	Ethyl Docetaxel
CAS No.	154044-47-0
Molecular Formula	C45H55NO14
Molecular Weight	834.0 g/mol
Synonyms	Docetaxel Impurity E; Docetaxel EP Impurity E; 7-Epi-10-oxo-docetaxel; 10-Oxo-7-epi-docetaxel; Ethyl 10-oxo-7-epi-docetaxel; (2R,3S)-N-Carboxy-3-phenylisoserine, 10-oxo-7-epi-docetaxel ethyl ester; Taxotere Impurity E
EINECS	Contact for details

Quality Control

Our Ethyl Docetaxel is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, detailing compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.