Description

4-Bromo-2,5-Dimethoxybenzene-1-Sulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual reactive sites—the sulfonyl chloride group and the bromo substituent—which enable precise and versatile molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for creating complex target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and sulfonyl functionalities.
• Material Science Research: Acts as a monomer or cross-linking agent in the creation of specialty polymers and advanced functional materials.
• Dye and Pigment Manufacturing: Intermediate for synthesizing complex organic dyes and pigments, especially sulfonated colorants.
• Chemical Biology & Proteomics: Useful as a labeling or modifying reagent for proteins and other biomolecules due to its electrophilic sulfonyl chloride group.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Item	Details
Product Name	4-Bromo-2,5-Dimethoxybenzene-1-Sulfonyl Chloride
CAS No.	153556-55-9
Molecular Formula	C8H8BrClO4S
Molecular Weight	315.57 g/mol
Synonyms	1-Bromo-2,5-dimethoxy-4-sulfonylchloridebenzene; 2,5-Dimethoxy-4-bromobenzenesulfonyl chloride; 4-Bromo-2,5-dimethoxybenzenesulfonyl chloride; 4-Bromo-2,5-dimethoxyphenylsulfonyl chloride; Benzenesulfonyl chloride, 4-bromo-2,5-dimethoxy-; 153556-55-9 (CAS); B2,5DMBSC
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,5-Dimethoxybenzene-1-Sulfonyl Chloride is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee product integrity and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.