Description

Paclitaxel C is a semi-synthetic derivative of the potent anticancer agent Paclitaxel, specifically identified by CAS No. 153415-45-3. This compound is of significant interest in pharmaceutical research and development due to its potential as a key intermediate or active pharmaceutical ingredient (API) for novel chemotherapeutic formulations. It is primarily utilized by pharmaceutical manufacturers, biotechnology research firms, and academic institutions engaged in oncology drug discovery and advanced cancer therapy development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of next-generation taxane-based chemotherapeutic agents.
• Oncology Research: Used as a reference standard or active compound in in vitro and in vivo studies to investigate mechanisms of action, efficacy, and resistance in various cancer cell lines.
• Drug Discovery & Development: Employed in high-throughput screening and structure-activity relationship (SAR) studies to design and optimize new anticancer molecules with improved potency or reduced side effects.
• API Manufacturing: Acts as an active pharmaceutical ingredient or a key building block in the production of specialized anticancer formulations, including liposomal or nanoparticle-based delivery systems.
• Analytical Standard: Provides a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical laboratories.

Basic Information

Item	Details
Product Name	Paclitaxel C
CAS No.	153415-45-3
Molecular Formula	C47H51NO14
Molecular Weight	853.91 g/mol
Synonyms	7-Epi-10-deacetylpaclitaxel; 10-Deacetyl-7-epipaclitaxel; 7-Epi-10-DAP; Paclitaxel Impurity C; Taxol C; NSC 716088; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecah-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl benzoate
EINECS	Contact for details

Quality Control

Our Paclitaxel C is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and stringent control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.